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Astrophysicist Neil deGrasse Tyson takes viewers on a head trip, examining questions about how the brain works in this NOVA special. Tyson visits with Penn Jillette and Teller to examine magic and the mind. Elsewhere, he explores the work of synesthesia researcher and neuroscientist David Eagleman, posing questions like, "What exactly is artificial intelligence?" and "How can the mind be controlled by magnets?"